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Rudolph's PediatricsRudolph's Pediatrics

Section 19. Disorders of the Ear, Nose, and Throat > 

Chapter 372. The Head, Face, and Neck

Congenital Anomalies of the Head and Neck

Craig S. Derkay and Michael J. Cunningham
Topics Discussed: branchial arch; congenital anomaly of head; congenital anomaly of neck; congenital anomaly of the thymus; congenital anomaly of the thyroid gland; dermoid cyst; developmental malformation of branchial arch; ear, nose, and throat; excision of thyroglossal cyst; face; first branchial arch; fourth branchial arch; head; neck; second branchial arch; sistrunk operation for thyroglossal cyst; third branchial arch; thyroglossal cyst.
Sections: Head and Neck Trauma, References.
Excerpt:"The critical period of cervicofacial growth and differentiation occurs between weeks 4 through 8 of embryologic development.1 The beginning of this stage is characterized by the appearance of the frontonasal process—the precursor of the forebrain and upper face—with development soon thereafter of the optic and otic vesicles; the nasal placodes; the primitive mouth, or stomodeum; and five ridges on the ventrolateral surface of the embryonic head, which is known as the branchial system. Many of the symmetrically paired skeletal and neuromuscular structures of the head and neck arise from the first (mandibular), second (hyoid), third (pharyngeal), and fourth (laryngeal) arches of this fetal branchial system (Table 372-1). The skull, facial, and neck bones have begun to ossify by the end of the eighth fetal week, which coincides with a recognizable human embryonic face with easily discernible ears, eyelids, cheeks, nose, and upper and lower lips.Lesions of the anterolateral neck are often of branchial system origin. Each of the four mesodermal branchial arches were separated from one another by an external cleft of ectodermal origin and by an internal pouch of endodermal origin with a thin epithelial plate separating cleft and pouch. Branchial cleft anomalies are classified by the likely arch of origin, with second branchial anomalies being most common.4 They form either sinuses, fistulas, or cysts. A sinus tract with either an external or internal opening..."
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