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Rudolph's PediatricsRudolph's Pediatrics

Section 19. Disorders of the Ear, Nose, and Throat > 

Chapter 370. Nose and Sinus

Ellen S. Deutsch and Cecille G. Sulman
Topics Discussed: ear, nose, and throat; inspiration; nose; paranasal sinuses; respiration.
Sections: Nasal Examination, Congenital Nasal Anomalies, Nasal Obstruction, Inflammation, and Rhinorrhea, Nasal Masses, Epistaxis: Etiology and Management, Acquired Nasal Abnormalities, Rhinosinusitis, Sinonasal Manifestations of Systemic Disease, Acknowledgment, References.
Excerpt:"The nose is the major portal of air exchange between the internal and external environment. Nasal functions include warming, lubricating, humidifying, filtering, stimulating, and regulating airflow. The roof of the nose also contains olfactory epithelium. In humans, the sense of smell contributes to the perception of taste, warns of impending hazards, and affects social interactions. The first sign of nasal development occurs at about 3 to 4 weeks of fetal life.1 It begins with nasal pits forming on the developing face that then invaginate to form the nasal sacs. The oronasal membrane separates the nasal sacs from the primitive oral cavity. The primitive nasal choanae communicate with the oral cavity when the membrane ruptures during the eighth week of gestation. As the membranous nasal cavities develop, neural crest cells migrate from the anterior skull base and proliferate in the facial processes to form the bony/cartilaginous skull base and nasal vaults, which are completely formed by the end of the 10th week. ..."
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