 |  | Rudolph's Pediatrics Section 17. Infectious Diseases > Part 7. Viral Infections > Chapter 318. MumpsDennis L. Murray |  |
Topics Discussed: infectious diseases; measles-mumps-rubella vaccine; mumps; mumps vaccine; mumps virus; orchitis; parotitis.
Sections: References.
Excerpt:"Mumps is a communicable systemic
viral illness usually characterized by parotitis. With the widespread
use of mumps vaccine, the disease has become less common. A significant
number of infections are asymptomatic.Humans are the only known natural hosts of mumps virus. The virus
can be recovered from patients with active disease from saliva, cerebrospinal
fluid (CSF), urine, blood, breast milk, and infected tissue.1,2 Mumps
virus infections are spread by respiratory droplet or by direct
contact with infected saliva. Virus can be demonstrated in respiratory
secretions up to 7 days before through 9 days after the onset of
parotitis.2 Secondary attack rates of mumps among
susceptible household contacts have been shown to be less than that
of measles or varicella, suggesting a less efficient transmission
of the mumps virus.3 The normal incubation period
is from 16 to 18 days (range 1225 days). In susceptible,
unimmunized populations, 60% to 70% of infections
are associated with parotitis.4 However, there
is a substantial subclinical attack rate produced by the mumps virus.
Approximately 20% of mumps infections may go unrecognized,
especially in adults, because they do not have evidence of parotitis.2,5 Given
the number of subclinical cases, information regarding a patient's
history of mumps infection is notoriously inaccurate. Mumps virus
infection is most communicable from 1 to 2 days prior to parotid
swelling until 5 days after..."
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