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Rudolph's PediatricsRudolph's Pediatrics

Section 17. Infectious Diseases > 

Part 7. Viral Infections > 

Chapter 318. Mumps

Dennis L. Murray
Topics Discussed: infectious diseases; measles-mumps-rubella vaccine; mumps; mumps vaccine; mumps virus; orchitis; parotitis.
Sections: References.
Excerpt:"Mumps is a communicable systemic viral illness usually characterized by parotitis. With the widespread use of mumps vaccine, the disease has become less common. A significant number of infections are asymptomatic.Humans are the only known natural hosts of mumps virus. The virus can be recovered from patients with active disease from saliva, cerebrospinal fluid (CSF), urine, blood, breast milk, and infected tissue.1,2 Mumps virus infections are spread by respiratory droplet or by direct contact with infected saliva. Virus can be demonstrated in respiratory secretions up to 7 days before through 9 days after the onset of parotitis.2 Secondary attack rates of mumps among susceptible household contacts have been shown to be less than that of measles or varicella, suggesting a less efficient transmission of the mumps virus.3 The normal incubation period is from 16 to 18 days (range 12–25 days). In susceptible, unimmunized populations, 60% to 70% of infections are associated with parotitis.4 However, there is a substantial subclinical attack rate produced by the mumps virus. Approximately 20% of mumps infections may go unrecognized, especially in adults, because they do not have evidence of parotitis.2,5 Given the number of subclinical cases, information regarding a patient's history of mumps infection is notoriously inaccurate. Mumps virus infection is most communicable from 1 to 2 days prior to parotid swelling until 5 days after..."
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