 |  | Color Atlas of Pediatric DermatologySection 21. Neoplastic Diseases | |
Topics Discussed: childhood cancer; leukemic infiltration of skin; medical oncology.
Sections: Hodgkin's Disease, Chloroma, Neuroblastoma, Metastatic, Langerhans' Cell Histiocytosis, Congenital Self-Healing Reticulohistiocytosis (Hashimoto-Pritzker Disease), Hypopigmented Mycosis Fungoides, Rosai-Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy), Basal Cell Carcinoma, Graft-versus Host Disease, Hydroa Vacciniforme-Like Cutaneous T-Cell Lymphoma (CTCL).
Excerpt:"A dermal infiltrate of leukemic cells results in the papulonodular lesions, or plaques, that are illustrated here. Such primary involvement of the skin is relatively rare in childhood leukemia. The wide variety of secondary manifestations of leukemia includes petechiae and ecchymoses and pyoderma gangrenosum. A polymorphonuclear dermal infiltrate termed Sweet's syndrome (see Fig. 13-18) may be associated with leukemia. In addition, children receiving chemotherapy are prone to bacterial and fungal infections of the skin, severe varicella, and ulcerative or chronic herpes simplex...."
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