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Rudolph's PediatricsRudolph's Pediatrics

Section 10. Transplantation > 

Chapter 129. Kidney Transplantation

Jodi M. Smith and Ruth A. McDonald
Topics Discussed: renal transplantation; transplantation.
Sections: Epidemiology, Management Issues in the Renal Transplant Patient, Outcomes of Renal Transplantion, References.
Excerpt:"Pediatric end-stage renal disease is successfully managed with either chronic dialysis or renal transplantation (see Chapters 477 and 478). Because transplantation promotes more normal growth and development compared with chronic dialysis, it is now the preferred approach to management.1,2 However, the required chronic immunosuppression exposes children to multiple complications and side effects (see Chapter 128), so management strategies attempt to minimize or eliminate immunosuppression while assuring graft survival. Many factors determine the optimal time for transplant in the individual patient, including the patient age, primary renal disease, psychosocial status, family dynamics, availability of a living donor versus deceased donor allograft, optimal immunosuppressive therapy, and maximization of growth and development...."
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