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Color Atlas & Synopsis of Pediatric Dermatology, 2eColor Atlas & Synopsis of Pediatric Dermatology, 2e

Section 1. Cutaneous Findings in the Newborn

Congenital Infections of the Newborn

Topics Discussed: congenital syphilis; congenital varicella syndrome; dermatology; neonatal herpes; neonatology; purpura 'blueberry muffin' rash.
Sections: Abnormalities of Subcutaneous Tissue.
Excerpt:"Neonatal herpes simplex infection is a potentially fatal disease. Neonatal herpes has a broad clinical spectrum and may be categorized into three patterns: localized infection confined to the skin, eyes, or mouth; CNS disease; and disseminated disease.Many infants with CNS and disseminated neonatal herpes do not develop cutaneous lesions.Type of Lesion Skin lesions begin as 2- to 8-mm macules or papules that progress to single or grouped vesicles that then rupture leaving an erosion or ulcer, which crusts over and heals (Fig. 1-15).Age Newborn.Congenital VZV SyndromeAge Newborn.Type Purpuric macules, papules, and nodules (Fig. 1-17).Age Within first months of life and after the age of 2.1. Aqueous crystalline penicillin G: (100000– 150000 units/kg) IM or (50000 units/kg IV q 8–12 hour) x 14 days.
2. Procaine penicillin G: (50000 units/kg IM q 24 hour x 10–14 days).
3. Benzathine penicillin G: (50000 units/kg IM x 1 dose).
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