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Pediatric Practice: GastroenterologyPediatric Practice: Gastroenterology

Section 4. Disorders of the Liver > 

Chapter 30. Liver Failure and Portal Hypertension

Elizabeth Mileti and Philip Rosenthal
Topics Discussed: gastroenterology and hepatology; hepatic encephalopathy; hypertension, portal; liver failure; liver failure, acute.
Sections: Pathogenesis, Clinical Presentation, Chronic Liver Failure and Portal Hypertension, Diagnosis, Treatment and Management, References.
Excerpt:"Acute liver failure (ALF) is a rare but devastating result of hepatic necrosis in previously healthy individuals. Hepatic function rapidly declines within days to weeks and is often complicated by coagulopathy, hepatic encephalopathy (HE), hypoglycemia, acute renal failure, sepsis, and gastrointestinal bleeding. These complications can lead to death with mortality rates up to 40% in the United States.1..."
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