Topics Discussed: acute illness; lead; lead poisoning; lead poisoning, nervous system, childhood.
Sections: Lead Poisoning: Introduction, Sources, Pharmacokinetics/Pathophysiology, Clinical Manifestations, Management, References.
- Lead poisoning causes multisystem clinical effects: headache, abdominal pain, constipation, vomiting, clumsiness, irritability, and drowsiness.
- Laboratory evaluation may demonstrate anemia, basophilic stippling, elevated erythrocyte protoporphyrins (EP), zinc protoporphyrins (ZPP), and elevated blood lead level (BLL).
- Management requires identification and removal of the source of exposure.
- Chelation with CaNa2EDTA, BAL, or succimer is dictated by BLL and severity of symptoms.
The content above is only an
excerpt. For full access, log into an existing user account below, purchase an annual subscription, or
purchase a short-term subscription to the complete website.
offers pediatrics students,
educators, and practioners access to leading McGraw-Hill texts, interactive imaging
content, exclusive multimedia, and flexible curricular tools.
Timed access to all of AccessPediatrics
24 hours for $29.95
48 hours for $49.95