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Pediatric Emergency MedicinePediatric Emergency Medicine

Part 4. Drugs of Abuse > 

Chapter 125. Gamma-Hydroxybutyrate

Jenny J. Lu, Timothy B. Erickson
Topics Discussed: acute illness; gamma hydroxybutyrate; gamma hydroxybutyrate overdose; pharmacology.
Sections: Gamma-Hydroxybutyrate: Introduction, Pharmacology, Pathophysiology, Diagnosis, Treatment, References, Suggested Reading.
Excerpt:"
  • The clinical picture of an abrupt onset of coma followed by rapid recovery within a few hours should arouse suspicion for GHB intoxication.
  • GHB levels are rarely available in a timely fashion.
  • Coingestions with alcohol and ecstasy are commonly associated with the recreational use of GHB.
  • Exposures to solvents or other products containing GHB precursors may lead to delayed GHB intoxication.
  • From a legal perspective, GHB levels are problematic
..."
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